吴为人

  发布时间: 2017-03-15   信息员:   

个人基本信息

吴为人,博士、教授、博士生导师

电话:0591-8378927283789176

电子信箱:wuwr@fafu.edu.cn649768350@qq.com

学术兼职

福建省遗传学会理事长,中国遗传学会理事

《分子植物育种》执行主编,《遗传》编委

荣誉称号

新世纪“百千万人才工程”国家级人选

享受国务院政府特殊津贴专家

福建省教学名师

主要研究方向

1、分子数量遗传

主要研究借助分子标记定位数量性状基因座(QTL)的统计分析方法,先后提出了联合定位、基于最小二乘的多性状定位复合区间定位、动态定位、三倍体胚乳性状QTL定位、印记QTL定位等方法。近年来,与生物信息学手段相结合,对利用高通量测序技术进行QTL定位分析的统计分析方法进行了研究,发展出了通过测序进行混合分离分析的QTL定位方法。目前,利用高通量测序进行数量性状基因定位已成为数量遗传学研究的热点和重要发展方向。

2、水稻遗传

采用基因(QTL)定位、图位克隆和功能分析的手段,研究水稻重要性状的遗传基础。利用一系列突变体,对水稻花器官发育的分子遗传机理开展了系统深入的研究,克隆了多个花器官发育关键基因。对水稻生育期、包穗、抗逆性、抗病性等也开展了分子遗传研究,克隆了包穗基因、耐盐基因、抗细条病基因等。这些研究对水稻育种具有潜在的应用价值。

发表论文

(仅列出SCI收录的论文;*号表示通讯作者)

1)Lan T, Zhang S, Liu T, Wang B, Guan H, Zhou Y, Duan Y, Wu W*. Fine mapping and candidate identification of SST, a gene controlling seedling salt tolerance in rice (Oryza sativa L.). Euphytica, 2015, 205: 269-274

2)Lan T, Zheng S, Yang L, Wang B, Zhang S, Tong Z, Chen Y, Chen S, Duan Y, Wu W*. Mapping of quantitative trait loci conferring resistance to bacterial wilt in tobacco (Nicotiana tabacum L.). Plant Breeding, 2014, 133: 672-677

3)Xie X, Chen Z, Cao J, Guan H, Lin D, Li C, Lan T, Duan Y, Mao D, Wu W*. Toward the positional cloning of qBlsr5a, a QTL underlying resistance to bacterial leaf streak, using overlapping sub-CSSLs in rice. PLoS ONE, 2014, 9(4): e95751. doi:10.1371/journal.pone. 0095751

4)Wen Y, Wu W*. Mapping of imprinted quantitative trait loci using immortalized F2 populations. PLoS ONE, 2014, 9(3): e92989. doi:10.1371/journal.pone.0092989

5)Xu Z, Wu W*. Comparative and joint analyses of gene expression profiles under drought and rewatering in Arabidopsis.Genetics and Molecular Research, 2013, 12(3): 3622-3629

6)Yang Z, Huang D, Tang W, Zheng Y, Liang K, Cutler AJ, Wu W*. Mapping of quantitative trait loci underlying cold tolerance in rice seedlings via high-throughput sequencing of pooled extremes. PLoS ONE, 2013, 8(7): e68433. doi:10.1371/journal.pone.0068433

7)Duan Y, Li S, Chen Z, Zheng L, Diao Z, Zhou Y, Lan T, Guan H, Pan R, Xue Y, Wu W*. Dwarf and Deformed Flower 1, encoding an F-box protein, is critical for vegetative and floral development in rice (Oryza sativa L.). Plant Journal, 2012, 72:829-842

8)Duan Y, Xing Z, Diao Z, Xu W, Li S, Du X, Wu G, Wang C, Lan T, Meng Z, Liu H, Wang F, Wu W*, Xue Y.Characterization of Osmads6-5, a null allele, reveals that OsMADS6 is a critical regulator for early flower development in rice (Oryza sativa L.). Plant Molicular Biology, 2012, 80:429-442

9)Tong Z, Yang Z, Chen X, Jiao F, Li X, Wu X, Gao Y, Xiao B, Wu W*. Large-scale development of microsatellite markers in Nicotiana tabacum and construction of a genetic map of flue-cured tobacco. Plant Breeding, 2012, 131: 674-680

10)Tong Z, Jiao T, Wang F, Li M, Leng X, Gao Y, Li Y, Xiao B, Wu W*. Mapping of quantitative trait loci conferring resistance to brown spot in flue-cured tobacco (Nicotiana tabacum L.). Plant Breeding, 2012, 131: 335-339

11)Huang B, Wu W*. Mapping of mutant gene prbs controlling poly-row-and-branched spike in barley (Hordeum vulgare L.). Agricultural Sciences in China, 2011, 10(10): 1501-1505

12)Lan T, Duan Y, Wang B, Zhou Y, Wu W*. Molecular cloning and functional characterization of a Na+/H+ antiporter gene from halophyte Spartina anglica. Turkish Journal of Agriculture and Forestry, 2011, 35: 535-543

13)Wang Y, Jiao T, Liu X, Lin F, Wu W*. Functional characterization of a NEM1-Like gene in Magnaporthe oryzae. Agricultural Sciences in China, 2011, 10(9): 101-105

14)Wang F, Wei H, Tong Z, Zhang X, Yang Z, Lan T, Duan Y, Wu W*.Knockdown of NtMed8, a Med8-like gene, causes abnormal development of vegetative and floral organs in tobacco (Nicotiana tabacum L.). Plant Cell Report, 2011, 30:2117-2129

15)Guan H, Duan Y, Liu H, Chen Z, Zhuo M, Zhuang L, Qi W, Pan R, Mao D, Zhou Y, Wang F, Wu W*. Genetic analysis and fine mapping of an enclosed panicle mutant esp2 in rice (Oryza sativa L.). Chinese Science Bulletin, 2011, 56(14): 1476-1480

16)Zheng Y, Zheng W, Lin F, Zhang Y, Yi Y, Wang B, Lu G, Wang Z, Wu W*. AVR1-CO39 is a predominant locus governing the broad avirulence of Magnaporthe grisea strain 2539 on cultivated rice (Oryza sativa L.). Molecular Plant Microbe Interaction, 2011, 24(1): 13-17

17)Chen X, Zhang G, Wu W*.Investigation and utilization of intron length polymorphisms in conifers. New Forests, 2010, DOI 10.1007/s11056-010-9229-5

18)Duan Y, Diao Z, Liu H, Cai M, Wang F, Lan T, Wu W*. Molecular cloning and functional characterization of OsJAG gene based on a complete-deletion mutant in rice (Oryza sativa L.). Plant Molecular Biology, 2010, 74: 605-615

19)Lan T, Wang B, Ling Q, Xu C, Tong Z, Liang K, Duan Y, Jin J, Wu W*. Fine mapping of cisc(t), a gene for cold-induced seedling chlorosis, and identification of its candidate in rice. Chinese Science Bulletin, 2010, 55: 3149-3153

20)Tang J, Yan J, Ma X, Teng W, Wu W et al. Dissection of the genetic basis of heterosis in an elite maize hybrid by QTL mapping in an immortalized F2 population. Theoretical and Applied Genetics, 2010, 120: 333-340

21)Zhao X, Yang L, Zheng Y, Xu Z, Wu W*. Subspecies-specific intron length polymorphism markers reveal clear genetic differentiation in common wild rice (Oryza rufipogon L.) in relation to the domestication of cultivated rice (O. sativa L.). Journal of Genetics and Genomics, 2009, 36: 435-442

22)Zheng Y, Zhang G, Lin F, Wang Z, Jin G, Yang L, Wang Y, Chen X, Xu Z, Zhao X, Wang H, Lu J, Lu G, Wu W*. Development of microsatellite markers and construction of genetic map in rice blast pathogen Magnaporthe grisea. Fungal Genetics & Biology, 2008, 45: 1340-1347

23)Huang D, Wu W, Abrams SR, Cutler AJ. The relationship of drought-related gene expression in Arabidopsis thaliana to hormonal and environmental factors. Journal of Experimental Botany, 2008, 59: 2991-3007

24)Wen Y, Wu W*. Experimental designs and statistical methods for mapping quantitative trait loci underlying triploid endosperm traits without maternal genetic variation. Journal of Heredity, 2008, 99(5): 546-551

25)Yang J, Wu W, Zhu J. Mapping interspecific genetic architecture in a host-parasite interaction system. Genetics, 2008, 178: 1737-1743

26)Yang L, Jin G, Zhao X, Zheng Y, Xu Z, Wu W*. PIP: a database of potential intron polymorphism markers. Bioinformatics, 2007, 23: 2174-2177

27)Wen Y, Wu W*. Interval mapping of quantitative trait loci underlying triploid endosperm traits using F3 seeds. Journal of Genetics and Genomics, 2007, 34(5): 429-436

28)Huang D, Jaradat MR, Wu W et al. Structural analogs of ABA reveal novel features of ABA perception and signaling in Arabidopsis. Plant Journal, 2007, 50: 414-428

29)Wang X, Zhu H, Jin G, Liu H, Wu W*, Zhu Jun. Genome-scale identification and analysis of LEA genes in rice (Oryza sativa L.). Plant Science, 2007, 172: 414-420

30)Tang J, Ma X, Teng W, Yan J, Wu W, Dai J, Li J. Detection of quantitative trait loci and heterotic loci for plant height using an immortalized F2 population in maize. Chinese Science Bulletin, 2007, 52(4): 477-483

31)Wu W*, Huang B. Strategy for the mapping of interactive genes using bulked segregant analysis method and Mapmaker/Exp software. Chinese Science Bulletin, 2006, 51(21): 2619-2623

32)Wen Y, Wu W*. Methods for mapping QTLs underlying endosperm traits based on random hybridization design. Chinese Science Bulletin, 2006, 51(16): 1976-1981

33)Wang X, Zhao X, Zhu J, Wu W*. Genome-wide investigation of intron length polymorphisms and their potential as molecular markers in rice (Oryza sativa L.). DNA Research, 2005, 12: 417-427

34)Wang X, Wu W*, Jin Gulei, Zhu Jun. Genome-wide identification of R genes and exploitation of candidate RGA markers in rice. Chinese Science Bulletin, 2005, 50(11):1120-1125

35)Huang D, Wu W, Zhou Y, Hu Z, Lu L. Microdissection and molecular manipulation of single chromosomes in woody fruit trees with small chromosomes using pomelo (Citrus grandis) as a model: I. construction of single chromosomal DNA libraries. Theoretical and Applied Genetics, 2004, 108: 1366-1370

36)Huang D, Wu W, Lu L. Microdissection and molecular manipulation of single chromosomes in woody fruit trees with small chromosomes using pomelo (Citrus grandis) as a model: II. cloning of resistance-gene analogs from single chromosomes. Theoretical and Applied Genetics, 2004, 108: 1371-1377

37)Hua J, Xing Y, Wu W et al. Single-locus heterotic effects and dominance by dominance interactions can adequately explain the genetic basis of heterosis in an elite rice hybrid. Proceedings of the National Academy of Sciences USA, 2003, 100: 2574-2579

38)Duan Y, Wu W*, Liu H et al. Genetic analysis and gene mapping of leafy head (lhd), a mutant blocking the differentiation of rachis branches in rice (Oryza sativa L.). Chinese Science Bulletin, 2003, 48(20): 2201-2205

39)Duan Y, Li W, Wu W et al. Genetic analysis and mapping of gene fzp(t) controlling spikelet differentiation in rice. Science in China (Ser. C), 2003, 46(3): 328-334

40)Lu Y, Sun X, Yao J, Chai Y, Zhao X, Zhang L, Song J, Pang Y, Wu W, Tang K. Isolation and expression of cold-regulated cDNA from chinese cabbage (Brassica pekinensis). DNA Sequence, 2003, 14(3): 219-222

41)Wu W*, Zhou Y, Li W et al. Mapping of quantitative trait loci based on growth models. Theoretical and Applied Genetics, 2002, 105: 1043-1049

42)Wu W*, Zhou Y, Li W. Comparison of potentials between genotype-based selection and genotypic value-based selection of quantitative traits. Chinese Science Bulletin, 2002, 47(24): 2080-2083

43)Zhou Y, Li W, Wu W* et al. Genetic dissection of heading time and its components in rice. Theoretical and Applied Genetics, 2001, 102: 1236-1242

44)Tang D, Wu W*, Li W et al. Mapping of QTLs conferring resistance to bacterial leaf streak in rice. Theoretical and Applied Genetics, 2000, 101: 286-291

45)Wu W*, Li W, Tang D et al. Time-related mapping of quantitative trait loci underlying tiller number in rice. Genetics, 1999, 151: 297-303

46)Wu W*, Li W. Joint mapping of quantitative trait loci using F2 populations. Theoretical and Applied Genetics, 1996, 93: 1156-1160

47)Wu W*, Li W. Model fitting and model testing in the method of joint mapping of quantitative trait loci. Theoretical and Applied Genetics, 1996, 92: 477-482

48)Wu W*, Li W. A new approach for mapping quantitative trait loci using complete genetic marker linkage maps. Theoretical and Applied Genetics, 1994, 89: 535-539

出版著作

方宣钧, 吴为人, 唐纪良. 《世纪之交863计划生物高技术丛书作物DNA标记辅助育种》,科学出版社, 2001

成果获奖

1) 作物复杂性状遗传分析与基因/QTL定位新方法研究,教育部自然科学奖二等奖(2012

2) 水稻分子标记辅助选择技术体系的建立与应用,福建省科学技术奖二等奖(2006

3) PCR技术快速鉴定sorghum属,福建省科学技术奖三等奖(2006

4) 细胞工程应用于水稻遗传育种的研究,福建省科学技术奖二等奖(2001